Sensing & Biosensing Application 

As the nanometer sized particles show extraordinary properties, the deliberate utilization of nanoparticles for sensing, biosensing and optical sensing have been explored. 

  • Electrochemical Sensors

The nanoparticles have been self-assembled on the electrode surface using thiol functionalized silicate network or composite materials on electrode platform for various electrochemical applications. The nanoparticle modified transducer has been used as a sensor for sensing of bioanalytes (e.g. Glucose, Ascorbic acid, Uric Acid, NADH, Neurotrasmitters(Dopamine) etc as well as used for speciation of environmental pollutants such as arsenic, mercury, chromium, lead and etc.

  • Electrochemical Biosensors

The integration of Nanoparticles and oxidase/dehydrogenase enzyme with the sol-gel derived silicate network or 2D matrix have carried out for the development of amperometric biosensors. The electrocatalytic activity of Nanoparticles has combined with the enzymatic activity of enzymes to develop enzymatic biosensor. The integrated biosensor shows fast and stable amperometric response towards analytes of interest. The biosrnsor has proved its potential application for real sample analysis.

  • Optical Sensors

The coinage metal nanoparticles with well-defined nanostructure have become one of the most active research areas in the past decades. The gold nanoparticles received considerable attention in different areas such as chemical and biological sensing, medical diagnostics and therapeutics and biological imaging, as these small particles exhibit strong surface plasmon resonance absorption. The fascinating optical properties of gold nanpparticles make it an ideal color-indicating candidate for signaling molecular recognition events. 

  • Photoelectrochemical Sensors

In fact, hybridization of semiconductor nanomaterials with plasmonic nanostructures has been widely investigated for their excellent performance in photocatalytic conversion. It was well observed that the catalytic efficiency of semiconductor materials get down to 10% during the photocatalytic process due to the recombination of photo generated excitons. In order to avoid this recombination and to increase the photocatalytic performance, the semiconductor nanoparticles are hybridized with plasmonic metal nanoparticles, while the plasmonic nanostructures play as a reservoir for the photo generated electrons and enhances the interfacial charge separation processes. Here we have given our effort for synthesis of photoelectro-active materials and explore the optical and electrochemical properties.

Representive Publications

  • B. Mohanty, K. K. Naik, S. Sahoo, B. Jena, B. Chakraborty, C. S. Rout, Bikash Kumar Jena*, “Efficient photoelectrocatalytic activity of CuWO4 nanoplates towards the oxidation of NADH driven in visible light” ChemistrySelect 2018, 3, 9008 – 9012. 

  • A. Dutta, A. K. Samantara, S. D. Adhikari, Bikash Kumar Jena,* and N. Pradhan* “Au Nanowires Striped Cu3P Platelet Photoelectrocatalysts” J. Phys. Chem. Lett., 2016, 7, 1077–1082. 

  • T. K. Behera, S. C. Sahu, B. Satpati, B. Bag, K. Sanjay, and Bikash Kumar Jena,* “Branched Platinum Nanostructures on Reduced Graphene: An excellent    Transducer for Nonenzymatic Sensing of Hydrogen Peroxide and Biosensing of  Xanthine” Electrochimica Acta, 2016, 206, 238-245. 

  • S. C. Sahu, T. K. Behera, A. Dash, B. L. Jena, A. Ghosh and Bikash Kumar Jena* “Highly Porous Pd Nanostructures and Reduced Graphene Hybrids: Excellent Electrocatalytic Activity towards Hydrogen Peroxide” New Journal of Chemistry 2016, 40, 1096-1099. 

  • A. K. Samantara, S. C. Sahu, B. Bag, B. Jena and Bikash Kumar Jena* “Photoelectrocatalytic Oxidation of NADH by Visible Light Driven Plasmonic Nanocomposites” J. Mater. Chem. A, 2014, 2, 12677-12680 

  • Priyabrata Pattanaik, Sushanta Kumar Kamilla, Jyoshnarani Mohapatra, Bikash Kumar Jena, Debi Prasad Das and Dilip Kumar Mishra, “Deposition of ZnO-valinomycin film on Al substrate for the detection of K+ in KOH solution," Nanosci. Nanotechnol. Lett. 2014, 6, 216–220. 

  • K. L. Adam, Bikash Kumar Jena, S. J. Percival, B. Zhang* “Highly-Sensitive Detection of Exocytotic Dopamine Release Using a Gold-Nanoparticle-Network Microelectrode.” Analytical Chemistry, 2011, 83, 920-927.

  • Bikash Kumar Jena. and C. Retna Raj* “Au nanoparticle decorated silicate network for the amperometric sensing of isoniazid.” Talanta, 2010, 80, 1653-1656. 

  • Bikash Kumar Jena, S. Ghosh, R. Bera, R. S. Dey, A. K. Das, and C. Retna Raj* “Bioanalytical applications of Au nanoparticles”. Recent Patents on Nanotechnology, 2010, 4, 41-57 . 

  • Bikash Kumar Jena. and C. Retna Raj* “Au nanoparticle decorated silicate network for the amperometric sensing of isoniazid.” Talanta, 2010, 80, 1653-1656. 

  • Bikash Kumar Jena S. J. Percival, B. Zhang* “Au Disk Nanoelectrode by Electrochemical Deposition in a Nanopore.” Analytical Chemistry, 2010, 82, 6737-6743. 

  • Bikash Kumar Jena and C. Retna Raj* “Enzyme Integrated Silicate-Pt Nanoparticle Architecture: A Versatile Biosensing Platform.” Biosensors and Bioelectronics, 2011, 26, 2960-2966. 

  • Bikash Kumar Jena and C. Retna Raj* “Highly sensitive and selective electrochemical detection of sub-ppb level chromium (VI) using nanosized gold particles” Talanta, 2008, 76, 161-165. 

  • Bikash Kumar Jena and C. Retna Raj* “Gold Nanoelectrode Ensembles for the Simultaneous Electrochemical Detection of Ultratrace Arsenite, Mercury and Copper” Analytical Chemistry 2008, 80, 4836-4844.

  • Bikash Kumar Jena and C. Retna Raj* “Optical Sensing of Biomedically Important Polyionic Drugs Using Nano-sized Gold Particles,” Biosensors and Bioelectronics, 2008, 23, 1285-1290.

  • Bikash Kumar Jena and C. Retna Raj* “Ultrasensitive Nanostructured Platform for the electrochemical sensing of Hydrazine”, Journal of Physical Chemistry C 2007, 111, 6228-6232. 

  • Bikash Kumar Jena and C. Retna Raj*, “Amperometric L-lactate Biosensor Based on Gold Nanoparticles”, Electroanalysis 2007, 19, 816-822.

  • Bikash Kumar Jena and C. Retna Raj*, “Enzyme-Free Amperometric Sensing of Glucose by Using Gold Nanoparticles” Chemistry-A European Journal 2006, 12, 2702-2708. 

  • Bikash Kumar Jena and C. Retna Raj* “Electrochemical Biosensor Based on Integrated Assembly of Dehydrogenase Enzymes and Gold Nanoparticles”, Analytical Chemistry 2006, 78, 6332-6339.

  • C. Retna Raj* and Bikash Kumar Jena “Efficient Electrocatalytic Oxidation of NADH at Gold Nanoparticles Self-assembled on Three-dimensional Sol-gel Network” Chemical Communication 2005, 2005-2007. 

CSIR-Institute of Minerals and Materials Technology