Biomedical Applications (Bioimaging, Cell Viability, Drug Delivery and Antibacterial )

  • Bioimaging, Cell Viability and Drug Delivery

The eco-friendly, nontoxic, photo chemically stable and nonblinking properties of carbon nanodots have been utilized for biomedical applications towards bioimaging and cell viability applications. The as synthesized carbon nanodots were employed for cell imaging studies and cell viability test with human embryonic kidney cell line (HEK 293 Cell). The anticancer drug Doxorubicin (DOX) was successfully loaded on the Carbon nanodots and explored their delivery efficiency to the target cells via in vitro treatment of cancerous cells. 

  • Antibacterial Applications

The antibacterial activity of as-synthesized branched Ag nanoflowers (SNFs) was investigated using agar well-diffusion method. The SNFs found to show potential antibacterial activity against Pseudomonas Aeruginosa, S. Faecalis, and Echerichia Coli bacterium of clinical interest

Representive Publications

  • A. K. Samantara, S. Maji, A. Ghosh, B. Bag, R. Dash, Bikash Kumar Jena,* “Good’s Buffer Derived Highly Emissive Carbon Quantum Dots: Excellent Biocompatible Anticancer Drug Carrier” J. Mater. Chem. B, 2016, 4, 2412-2420. 

  • Bikash Kumar Jena*, B. K. Mishra, S. Bohider “Synthesis of branched Ag nanoflowers based on a bioinspired technique: Their surface enhanced Raman scattering and antibacterial activity.” Journal of Physical Chemistry C, 2009, 113, 14753-14758.

CSIR-Institute of Minerals and Materials Technology